Whilst reduced-count MBL seldom progresses to CLL, substantial-rely MBL progresses to CLL requiring therapy in a fee of 1% to two% per annum. Superior-count MBL is distinguished from Rai 0 CLL based on whether or not the B-mobile rely is earlier mentioned or underneath five × 109/L. While men and women with both of those high-depend MBL and CLL Ra